Imaging brain microstructure with diffusion MRI: practicality and applications

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Diffusion MRI of Brain Connectivity and Microstructure:

What is a “diffusion coefficient” or “diffusion tensor” in living tissue, anyway? While the measurement of the self-diffusivity in an NMR tube represents a "gold standard", in complex media particularly in living tissue, water “diffusivity” ceases to have a clear meaning or definition. The apparent diffusion coefficient (ADC) and apparent diffusion tensor (ADT) concepts were introduced to answe...

متن کامل

Imaging lung microstructure in mice with hyperpolarized 3He diffusion MRI.

Quantitative measurement of lung microstructure is of great significance in assessment of pulmonary disease, particularly in the earliest stages. The technique for MRI-based 3He lung morphometry was previously developed and validated for human lungs, and was recently extended to ex vivo mouse lungs. The technique yields accurate, quantitative information about the microstructure and geometry of...

متن کامل

Model-based super-resolution of diffusion MRI for microstructure imaging

PURPOSE This work develops a super-resolution reconstruction (SRR) technique that constructs isotropic high-resolution (HR) diffusion-weighted images (DWI) from multiple anisotropic lowresolution (LR) acquisitions (Fig 1). Isotropic HR DWIs enable the mapping of tissue microstructure for fine brain structures, such as the subfields of hippocampus. Direct acquisition of such images require prohi...

متن کامل

Diffusion-weighted MRI for body imaging applications

Diffusion is the thermally induced motion of water molecules in biological tissues, called Brownian motion. Diffusion-weighted MRI (DWI) by means of apparent diffusion coefficient (ADC) calculation can be used for in vivo quantification of the combined effects of capillary perfusion and diffusion. With the advent of echoplanar imaging (EPI), DWI of the abdomen has become possible with fast imag...

متن کامل

Contrast and stability of the axon diameter index from microstructure imaging with diffusion MRI

The ActiveAx technique fits the minimal model of white matter diffusion to diffusion MRI data acquired using optimized protocols that provide orientationally invariant indices of axon diameter and density. We investigated how limitations of the available maximal gradient strength (Gmax) on a scanner influence the sensitivity to a range of axon diameters. Multishell high-angular-diffusion-imagin...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: NMR in Biomedicine

سال: 2017

ISSN: 0952-3480,1099-1492

DOI: 10.1002/nbm.3841